Age-related macular degeneration is the most important cause of visual impairment in the elderly. The non-exudative or dry form progresses slowly, the exudative or wet form rapidly (within weeks or months). Refer a patient with suspected exudative form of the disease without delay for investigations and treatment. Also consider the significance of the disease in the patients' daily life.
Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries.There have been rapid developments of therapies that today can halt or even reverse aspects of vision loss resulting from AMD among those most severely affected, and there is promise of future therapies that may prevent vision loss. This book provides an overview about AMD; an update on the current understanding of AMD, pathophysiology, the use of diagnostic tests, the management of both non-neovascular and neovascular AMD as well as future directions in treatment and its limitations. It also looks into the future with potential treatment options that are now under investigation in clinical trials.
Showcases exudative and nonexudative AMD treatment techniques using argon and diode lasers, submacular and macular translocation surgery, photodynamic therapy, radiation, feeder vessel treatment, thermotherapy, and antiangiogenesis drugs. Includes 160 color illustrations. Showcases exudative and nonexudative AMD treatment techniques using argon and diode lasers, submacular and macular translocation surgery, photodynamic therapy, radiation, feeder vessel treatment, thermotherapy, and antiangiogenesis drugs. Age-Related Macular Degeneration examines newly developed treatments for CNV immune mechanisms of AMD histopathology of various stages of AMD epidemiology and risk factors for AMD, CNV, and geographic atrophy genetics of AMD risk reduction modalities ICG and OCT imaging clinical trials and research protocols quality of life assessments and the psychosocial aspects of AMD potential applications of a retinal prosthesis retinal pigment epithelium transplantation With 1425 references, Age-Related Macular Degeneration will benefit clinical ophthalmologists, pathologists, physiologists, and pharmacologists; optometrists; cell and molecular biologists and biochemists; retinal specialists; AMD researchers; and graduate and medical school students in these disciplines.
|Author||: Allen C. Ho,Carl D. Regillo|
|Publisher||: Springer Science & Business Media|
|Release Date||: 2011-08-09|
|ISBN 10||: 9781461401254|
|Pages||: 184 pages|
Age-Related Macular Degeneration: Diagnosis and Treatment is written by two leading experts from Wills Eye Hospital. Covering the latest therapies and treatments developed in the last few years, this is a concise yet highly illustrated and practical text that guides the clinician through diagnosis and treatment of the leading cause of blindness in older Americans.
AGE-RELATED MACULAR DEGENERATION provides ophthalmologists with the first comprehensive volume on Age-Related Macular Degeneration (AMD). This extensive text discusses the disease, its progression, methods of diagnosis, treatment strategies, translocation and transplantation surgeries, and laser procedures. It includes significant chapters on pathology, replete with over 150 color slides showing the histopathologic features of AMD; Optical Coherence Tomography, with over 50 color images; Laser Prophylaxis and Laser Treatment; Radiation Therapy; and RPE Transplantation. With expert direction from the renowned Scheie Eye Institute and over 590 images (over 300 in color), the book presents the most up-to-date information available in one volume. Provides the first authoritative, multi-contributed reference on the leading cause of blindness in the United States and western nations. Features a concise, heavily illustrated format with color photographs - a valuable diagnostic tool for all general ophthalmologists and retinal specialists. Uses an interdisciplinary approach to AMD research and management, and includes contributions from clinicians and researchers who are experts in those disciplines. Includes topics relevant to every-day use, as well as areas still being evaluated for usefulness to allow the reader to understand the present approach to AMD as well as developing methods. Features over 430 color images in full color so the reader understands more fully the pathology of the disease. Assimilates current research on pathobiology, potential inhibitors for the progression of the disease, current and new imaging methods, and new therapeutic and pharmacologic modalities to provide the reader with a comprehensive understanding of the disease and the approaches to managing it. Edited by three authorities on macular degeneration from the world-renowned Scheie Eye Institute.
|Author||: Gabriel Coscas|
|Publisher||: Springer Science & Business Media|
|Release Date||: 2009-07-25|
|ISBN 10||: 3642014674|
|Pages||: 389 pages|
Rapid or even dramatic progress has been made in the field of AMD over recent years, leading to a constant revision of basic concepts. A wide range of fundus imaging modalities are now available, and this book explains the respective value of each technique. The information provided by OCT is presented logically by comparison with plain films, autofluorescence, fluorescein angiography, or indocyanine green angiography. Meticulous biomicroscopic examination of macular changes and the essential value of fluorescein angiography for the detection of anatomical alterations of the macula and for precise evaluation of lesions and their course by indocyanine green angiography have naturally led the author Gabriel Coscas to analyze the new data provided by OCT.
Macular degeneration is diagnosed as either dry (non-neovascular) or wet (neovascular). Neovascular refers to growth of new blood vessels in an area, such as the macula, where they are not supposed to be. The dry form is more common than the wet, with about 85%-90% patients diagnosed. The wet form of the disease usually leads to more serious vision loss. Different forms of macular degeneration may occur in younger patients. These non-age related cases may be linked to heredity, diabetes, nutritional deficits, head injury, infection, or other factors. This new book presents the latest research from around the world.
Choroidal Disorders provides an overview on various chorioretinal disorders with a special emphasis on choroidal imaging. As our understanding of the choroid has significantly improved with the development of advanced optical coherence tomography (OCT) and its role in posterior segment diseases is gaining new significance, this book focuses on the related improvements, diagnostic capabilities, management and prognosis of various chorioretinal disorders. It covers conventional techniques, such as ultrasonography and indocyanine green angiography as well as the most advanced techniques, including enhanced depth imaging OCT, swept source OCT, and OCT angiography. Concise overview of various chorioretinal disorders, with special emphasis on choroidal imaging Written for practitioners and researchers in sensory systems (vision), ophthalmologists, and retina specialists Covers the most advanced imaging techniques in choroidal disorders, such as enhanced depth imaging OCT, swept source OCT, and OCT angiography
Describes the symptoms of AMD, or age-related macular degeneration, and discusses risk factors, treatments, and coping strategies.
The Handbook of Nutrition, Diet and the Eye is the first book to thoroughly address common features and etiological factors in how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss can be devastating. One of the biggest contributors to complete vision loss in the western hemisphere is diabetes, precipitated by metabolic syndrome. In some developing countries, micronutrient deficiencies are major contributory factors to impaired vision. However, there are a range of ocular defects that have either their origin in nutritional deficiencies or excess or have been shown to respond favorably to nutritional components. The eye from the cornea to the retina may be affected by nutritional components. Effects may be physiological or molecular. This book represents essential reading for nutritionists, dietitians, optometrists, ophthalmologists, opticians, endocrinologists, and other clinicians and researchers interested in eye health and vision in general. Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of nutrition, ocular health, and disease issues Provides a common language for nutritionists, nutrition researchers, optometrists, and ophthalmologists to discuss how dietary and nutritional factors, and related diseases and syndromes affect the eye Preclinical, clinical, and population studies will help nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations
Age-related macular degeneration (AMD) is the leading cause of blindness in individuals older than 65 years of age. The authors of this book discuss the role of genetics, sunlight, diet, cardiovascular factors, smoking and alcohol as possible risk factors for AMD. Furthermore, the dry form is more common and accounts for about 85-90% of AMD patients in the USA, while Japanese AMD patients predominantely progress to wet-form or polypoidal choroidal vasculopathy (PCV). The function of a serine protein gene, HTRA1, in wet-form AMD patients is explored in detail. Conversely, the final chapter evaluates the therapeutic effects of high omega-3 fatty acids as anti-inflammatory agents in dry AMD patients. The preliminary findings indicate a promising therapeutic regime for dry AMD and perhaps for other retinopathies as well.
Age-related macular degeneration (AMD) is a progressive disease of the retina that develops when the light-sensing cells in the central area of vision (the macula) stop working and eventually die. Thought to be caused by a combination of genetic and environmental factors, the disease is the leading cause of blindness in people over 50. In 1995, Dan Roberts retired from teaching to help others who also suffered from macular degeneration. Roberts has established support networks for AMD patients and provided free presentations about vision impairment at schools, community organizations, and support groups across the country. The First Year: Age-Related Macular Degeneration is an essential resource for those who want to be an informed, active participant in the management of their condition.
The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration. Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.
Aging research on the human eyes crosses all areas of ophthalmology and also relies upon biological, morphological, physiological, and biochemical tools for its study. This book reviews all aspects of human eye aging. In addition to descriptions of age-related changes in almost all the structures of the human eyes, the authors also include interesting accounts of personal experiments and data. It provides an extensive panorama of what happens during aging in the eye.
This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.
In this new and updated edition, a respected ophthalmologist with macular degeneration shows you how to get the most from the sight you have.
Stay up to date with the latest developments in your field with the highly-anticipated second edition of Age-Related Macular Degeneration. This comprehensive text covers recent advances in pathophysiology, diagnosis, and treatment including promising new developments that will affect your patient care. Dr. Virgil Alfaro and his colleagues at Retina Consultants of Charleston bring you their expertise in the areas of basic science, imaging, prevention, treatment, and more. Features: Learn from a renowned group of retina surgeons who address all aspects of management, including anatomy, physiology, and pathophysiology; imaging of the macula in ARMD, prevention measures and treatment; and future directions in the field. Gain a solid foundation in intravenous fluorescein angiography, indocyanine green angiography, and optical coherence tomography, as well as antiVEGE therapy and related new drugs, optimizing your diagnosis and treatment options. Understand the significant change in the classification system of choroidal neovascular membranes in ARMD. Get up-to-date information on treating ARMD secondary to geographic atrophy through cell transplantation and pharmacologic therapies. Easily visualize key aspects of ARMD thanks to high-quality illustrations and photographs. Find the information you need quickly by referencing individual chapters that offer comprehensive and inclusive coverage of the topic at hand.