advanced 3d printed systems and nanosystems for drug delivery and tissue engineering

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Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering
Author : Lisa C. du Toit,Pradeep Kumar,Yahya E. Choonara,Viness Pillay
Publisher : Elsevier
Release Date : 2020-03-08
ISBN 10 : 0128184728
Pages : 316 pages

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient Explores the current generation of nanostructured 3D printed medical devices Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

3D Printed Microfluidic Devices
Author : Savas Tasoglu,Albert Folch
Publisher : MDPI
Release Date : 2019-01-10
ISBN 10 : 3038974676
Pages : 211 pages

This book is a printed edition of the Special Issue "3D Printed Microfluidic Devices" that was published in Micromachines

Nanomaterials for Theranostics and Tissue Engineering
Author : Filippo Rossi,Alberto Rainer
Publisher : Elsevier
Release Date : 2020-08-22
ISBN 10 : 0128178396
Pages : 322 pages

Nanomaterials for Theranostics and Tissue Engineering: Techniques, Trends and Applications provides information on the major methodologies for the application of nanomaterials in the medical field. In recent years, nanotechnology for medicine, commonly known as bionanotechnology, or nanomedicine, has revolutionized various types of medical treatment. This book is intended for practicing engineers and scientists, and includes detailed, readily applicable protocols. It focuses on 4 major themes, including the synthesis of nanosystems for controlled drug delivery, nanotechnology-enhanced sensing systems, the application of nanotechnologies to the synthesis of novel biomaterials, and safety issues related to the application of medicinal nanotechnology. Provides a comprehensive overview on how nanotechnology is being used to create new tissue engineering techniques Covers, in detail, the physicochemical fundamentals of bionanotechnologies Explores major applications in the fields of theranostics and tissue engineering Assesses important challenges and safety issues related to the implementation of nanotechnology in medicine

Biomimetic Nanoengineered Materials for Advanced Drug Delivery
Author : Afeesh Rajan Unnithan,Arathyram Ramachandra Kurup Sasikala,Cheol Sang Kim,Chan Hee Park
Publisher : N.A
Release Date : 2019-10
ISBN 10 : 9780128149447
Pages : 445 pages

Biomimetic Nanoengineered Materials for Advanced Drug Delivery is an indispensable guide for new developments in biomimetic nanoengineering for advanced drug delivery applications. Focusing on the fundamentals of a new type of nanocarriers for drug delivery in the most recent miRNA therapeutics, the book provides readers with detailed knowledge from the basics, to the most recent innovations. Early chapters of the book discuss a range of drug delivery techniques, including nanofibers, biomimetic polymers, 3D bioprinting, nanotechnology and radiofrequency sensitive nanocarriers. Later chapters explore miRNA therapeutics, magnetic nanoparticles, nanogel-based and ROS-mediated drug delivery systems. The book is a vital reference for biomaterials and nanomedicine researchers and clinicians with an interest in advanced drug delivery. Analyzes nanoparticle-plasma protein interactions, making it one of the first books on this topic Includes the latest trends in nanotherapeutic drug delivery Presents comprehensive chapters that cover a specific drug delivery carrier and its mode of operation, stimuli and the target site of action Provides an essential tool for researchers in nanomedicine and nanobiomaterials

Nanotechnologies in Preventive and Regenerative Medicine
Author : Vuk Uskokovic
Publisher : Elsevier
Release Date : 2017-11-22
ISBN 10 : 0323480640
Pages : 616 pages

Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage Explains how nanomaterials can be manipulated to create more effective drug treatments Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

3D Printing in Medicine
Author : Deepak M Kalaskar
Publisher : Woodhead Publishing
Release Date : 2017-04-17
ISBN 10 : 0081007264
Pages : 178 pages

3D Printing in Medicine examines the emerging market of 3D-printed biomaterials and its clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The book begins with a discussion of the fundamentals of 3D printing, including topics such as materials, and hardware. Chapters go on to cover applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing and 3D cell and organ printing. The concluding chapters in the book review the applications of 3D printing in diagnostics, drug development, 3D-printed disease models and 3D printers for surgical practice. With a strong focus on the translation of 3D printing technology to a clinical setting, this book is a valuable resource for scientists and engineers working in biomaterial, biomedical, and nanotechnology based industries and academia. Provides a comprehensive and authoritative overview of all the medical applications of 3D printing biomaterials and technologies Focuses on the emerging market of 3D printed biomaterials in clinical applications Reviews both commercial and under development materials, tools, their applications, and future evolution

Nanoengineered Biomaterials for Advanced Drug Delivery
Author : Masoud Mozafari
Publisher : Elsevier
Release Date : 2020-06-17
ISBN 10 : 0081029861
Pages : 820 pages

Nanoengineered Biomaterials for Advanced Drug Delivery explores the latest advances in the applications of nanoengineered biomaterials in drug delivery systems. The book covers a wide range of biomaterials and nanotechnology techniques that have been used for the delivery of different biological molecules and drugs in the human body. It is an important resource for biomaterials scientists and engineers working in biomedicine and those wanting to learn more on how nanoengineered biomaterials are being used to enhance drug delivery for a variety of diseases. Nanoengineered biomaterials have enhanced properties that make them more effective than conventional biomaterials as both drug delivery agents, and in the creation of new drug delivery systems. As nanoengineering becomes more cost-effective, nanoengineered biomaterials have become more widely used within biomedicine. Offers an informed overview on how nanoengineering biomaterials enhance their properties for drug delivery applications Discusses the major applications of nanoengineered biomaterials for drug delivery Outlines the major challenges for successfully implementing nanoengineered biomaterials into existing drug delivery systems

Nanobiomaterials Science, Development and Evaluation
Author : Mehdi Razavi,Avnesh Thakor
Publisher : Woodhead Publishing
Release Date : 2017-05-22
ISBN 10 : 0081009682
Pages : 340 pages

Nanobiomaterials Science, Development and Evaluation examines the practical aspects of producing nanostructured biomaterials for a range of applications. With a strong focus on materials, such as metals, ceramics, polymers, and composites, the book also examines nanostructured coatings and toxicology aspects. Chapters in Part One look at materials classes and their synthesis with information on all major material groups. Part Two focuses on nanostructured coatings and practical aspects associated with the use of nanobiomaterials in vivo. This book brings together the work of international contributors who are actively engaged on the forefront of research in their respective disciplines, and is a valuable resource for materials scientists in academia, industry, and all those who wish to broaden their knowledge in the allied field. Focuses on the synthesis and evaluation techniques for a range of nanobiomaterials Examines nanostructured inorganic coatings for biomaterials Discusses issues related to the toxicology of nanobiomaterials Presents the practical aspects of nanobiomaterials

Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy
Author : Challa S.S.R. Kumar
Publisher : Springer Nature
Release Date : 2019-11-22
ISBN 10 : 3662595966
Pages : 464 pages

Ninth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Electrospinning: Nanofabrication and Applications
Author : Bin Ding,Xianfeng Wang,Jianyong Yu
Publisher : William Andrew
Release Date : 2018-11-12
ISBN 10 : 0128134410
Pages : 832 pages

Electrospinning: Nanofabrication and Applications presents an overview of the electrospinning technique, nanofabrication strategies and potential applications. The book begins with an introduction to the fundamentals of electrospinning, discussing fundamental principles of the electrospinning process, controlling parameters, materials and structures. Nanofabrication strategies, including coaxial electrospinning, multi-needle electrospinning, needleless electrospinning, electro-netting, near-field electrospinning, and three-dimensional macrostructure assembling are also covered. Final sections explore the applications of electrospun nanofibers in different fields and future prospects. This is a valuable reference for engineers and materials scientist working with fibrous materials and textiles, as well as researchers in the areas of nanotechnology, electrospinning, nanofibers and textiles. Explores controllable fabrication of electrospun nanomaterials and their multifunctional applications Explains the electrospinning technique as used in nanofabrication and nanofibers Outlines the applications of electrospun nanofibrous materials in tissue engineering, filtration, oil-water separation, water treatment, food technology, supercapacitors, sensors and so on

3D Printing with Biomaterials
Author : A.J.M. van Wijk,I. van Wijk
Publisher : IOS Press
Release Date : 2015-01-15
ISBN 10 : 1614994862
Pages : 86 pages

Additive manufacturing or 3D printing, manufacturing a product layer by layer, offers large design freedom and faster product development cycles, as well as low startup cost of production, on-demand production and local production. In principle, any product could be made by additive manufacturing. Even food and living organic cells can be printed. We can create, design and manufacture what we want at the location we want. 3D printing will create a revolution in manufacturing, a real paradigm change. 3D printing holds the promise to manufacture with less waste and energy. We can print metals, ceramics, sand, synthetic materials such as plastics, food or living cells. However, the production of plastics is nowadays based on fossil fuels. And that’s where we witness a paradigm change too. The production of these synthetic materials can be based also on biomaterials with biomass as feedstock. A wealth of new and innovative products are emerging when we combine these two paradigm changes: 3D printing and biomaterials. Moreover, the combination of 3D printing with biomaterials holds the promise to realize a truly sustainable and circular economy.

3D Printing Technology in Nanomedicine
Author : Nabeel Ahmad,P. Gopinath,Rajiv Dutta
Publisher : Elsevier
Release Date : 2019-03-30
ISBN 10 : 0128158913
Pages : 202 pages

3D Printing Technology in Nanomedicine provides an integrated and introductory look into the rapidly evolving field of nanobiotechnology. It demystifies the processes of commercialization and discusses legal and regulatory considerations. With a focus on nanoscale processes and biomedical applications, users will find this to be a comprehensive resource on how 3D printing can be utilized in a range of areas, including the diagnosis and treatment of a variety of human diseases. Examines the emerging market of 3D-printed biomaterials and their clinical applications, with a particular focus on both commercial and premarket tools Examines the promising market of 3D-printed nanoparticles, nanomaterial, biomaterials, composite nanomaterial and their clinical applications in the cardiovascular and chemotherapy realms Develops the concept of integrating different technologies along the hierarchical structure of biological systems

3D Printing of Pharmaceuticals
Author : Abdul W. Basit,Simon Gaisford
Publisher : Springer
Release Date : 2018-08-06
ISBN 10 : 3319907557
Pages : 240 pages

3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.

Micro- and Nanosystems for Biotechnology
Author : J. Christopher Love
Publisher : John Wiley & Sons
Release Date : 2016-03-07
ISBN 10 : 3527801294
Pages : 302 pages

Emphasizing their emerging capabilities, this volume provides a strong foundation for an understanding of how micro- and nanotechnologies used in biomedical research have evolved from concepts to working platforms. Volume editor Christopher Love has assembled here a highly interdisciplinary group of authors with backgrounds ranging from chemical engineering right up to materials science to reflect how the intersection of ideas from biology with engineering disciplines has spurred on innovations. In fact, a number of the basic technologies described are reaching the market to advance the discovery and development of biopharmaceuticals. The first part of the book focuses on microsystems for single-cell analysis, examining tools and techniques used to isolate cells from a range of biological samples, while the second part is dedicated to tiny technologies for modulating biological systems at the scale of individual cells, tissues or whole organisms. New tools are described which have a great potential for (pre)clinical development of interventions in a range of illnesses, such as cancer and neurological diseases. Besides describing the promising applications, the authors also highlight the ongoing challenges and opportunities in the field.

Strategies to Modify the Drug Release from Pharmaceutical Systems
Author : Marcos Luciano Bruschi
Publisher : Woodhead Publishing
Release Date : 2015-06-16
ISBN 10 : 0081001126
Pages : 208 pages

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. Addresses the principles, systems, applications and advances in the field of drug delivery Highlights the mathematical and physicochemical principles related to strategies Discusses drug release and its possible modifications

Composite Nanoadsorbents
Author : George Z. Kyzas,Athanasios C. Mitrpoulos
Publisher : Elsevier
Release Date : 2018-11-30
ISBN 10 : 0128141336
Pages : 385 pages

Composite Nanoadsorbents discusses the most recent advances in the field, including promising techniques for waste water decontamination and the advantages and drawbacks of nanoadsorbents in these applications. The implications of nanoadsorbents to public health and future developments for facilitating environmental sustainability are also discussed. New approaches for nanomaterials are analyzed, focusing on the effect of nanotechnology in adsorption applications. The effectiveness of nanosized materials is evaluated, along with cost factors and new synthesis routes of composite nanomaterials. Combining the areas of nanotechnology, adsorption, and composite surface chemistry, the synthesis, modifications and applications of nanotechnology in the adsorption process are demonstrated. Edited by a prolific expert in the field, this book will be a valuable resource for researchers, postgraduate students and professionals in the fields of nanotechnology, adsorption and materials synthesis. Bridges the gap between theory and application of composite nanoadsorbents Provides an understanding of the benefits of nanoadsorbents and their cost, efficiency and novelty Includes material on inorganic nanoadsorbents and carbon nanotubes

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy
Author : Muhammad Raza Shah,Muhammad Imran,Shafi Ullah
Publisher : Elsevier
Release Date : 2019-07-13
ISBN 10 : 0128163119
Pages : 310 pages

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites. This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment. Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers

Nanomaterials in Tissue Engineering
Author : A K Gaharwar,S Sant,M J Hancock,S A Hacking
Publisher : Elsevier
Release Date : 2013-07-31
ISBN 10 : 0857097237
Pages : 468 pages

Nanomaterial technologies can be used to fabricate high-performance biomaterials with tailored physical, chemical, and biological properties. They are therefore an area of interest for emerging biomedical technologies such as scaffolding, tissue regeneration, and controlled drug delivery. Nanomaterials in tissue engineering explores the fabrication of a variety of nanomaterials and the use of these materials across a range of tissue engineering applications. Part one focuses on the fabrication of nanomaterials for tissue engineering applications and includes chapters on engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials. Part two goes on to highlight the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering. Finally, the use of nanomaterials in hard tissue engineering applications, including bone, dental and craniofacial tissue engineering is discussed in part three. Nanomaterials in tissue engineering is a standard reference for researchers and tissue engineers with an interest in nanomaterials, laboratories investigating biomaterials, and academics interested in materials science, chemical engineering, biomedical engineering and biological sciences. Explores the fabrication of a variety of nanomaterials and their use across a range of tissue engineering applications Examines engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials Highlights the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering

Nanotechnology Applications for Cancer Chemotherapy
Author : Sanyog Jain,Kaisar Raza,Ashish Kumar Agrawal,Ankur Vaidya
Publisher : Elsevier
Release Date : 2020-10-01
ISBN 10 : 0128178477
Pages : 702 pages

Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier-based therapeutic approaches to modulate the progression of the disease. In addition, this book also explores the evolving targeting approaches specific to the cancer site and type. The scope of the book is not limited to targeted drug delivery for various cancers, but also explores the advancements in cancer imaging and diagnostics employing the nanotechnological tools. Emphasis has been given on the important evaluation techniques like in-vitro cell culture and in-vivo animal models to assess the performance of cancer nanomedicines. The book includes clinical study reports of various drug moieties explored using variety of nanoconstructs in myriad cancer conditions with the input of global market and pharmacoeconomics. Discusses how organic and inorganic nanoplatforms are being used in cancer treatment Shows how nanotechnology is being used to create new and more accurate diagnostic tools Surveys the current generation of cancer nanomedicines, assessing their advantages and challenges

Principles of Regenerative Medicine
Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publisher : Academic Press
Release Date : 2010-12-16
ISBN 10 : 9780123814234
Pages : 1202 pages

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs